Dengue: Causes, Symptoms, Pathophysiology, Treatment and Home Remedies

Dengue fever is one of the most serious mosquito-borne viral infections worldwide. Each year, millions of people across tropical and subtropical regions are affected. Most cases are mild, but severe dengue can become life-threatening without proper care. Understanding its causes, symptoms, how it affects the body, and what treatments and home remedies can help is crucial for prevention and recovery. This article covers all these aspects in depth.


Definition of Dengue

Dengue is an acute viral infection transmitted to humans through the bite of an infected Aedes aegypti mosquito. These mosquitoes are most active during the early morning and late evening hours. Because of the intense joint and muscle pain it causes, dengue is sometimes called “breakbone fever.” Unlike some diseases confined to rural areas, dengue thrives in both urban and rural settings.

Key points:

  • Viral: caused by dengue virus, not bacteria.
  • Vector-borne: spread via mosquito bites.
  • Systemic: affects multiple body systems, not just one area.

Causes of Dengue

The Virus

The dengue virus belongs to the Flaviviridae family and exists as four distinct but closely related serotypes: DEN-1, DEN-2, DEN-3, and DEN-4. Immunity to one serotype does not protect against the others; in fact, a second infection with a different serotype increases the risk of severe dengue.

The Vector: Aedes Mosquito

The main transmitter is the female Aedes aegypti mosquito. It:

  • Breeds in clean, stagnant water in flower pots, old tires, open water tanks, and discarded containers.
  • Bites primarily during the day, especially at dawn and dusk.
  • Prefers urban areas where people live close together.

Mode of Transmission

The virus spreads indirectly:

  1. A mosquito bites an infected person during the period when the virus is circulating in their blood.
  2. The virus multiplies inside the mosquito for about 8–12 days.
  3. That mosquito then bites a healthy person, injecting the virus into their bloodstream.

There is no direct person-to-person spread.


Symptoms of Dengue

Symptoms appear 4–10 days after being bitten by an infected mosquito. They range from mild to severe.

Common Symptoms

  • High Fever: sudden onset, up to 104°F (40°C).
  • Severe Headache: often behind the eyes.
  • Muscle and Joint Pain: called “breakbone fever” because of its severity.
  • Nausea and Vomiting.
  • Skin Rash: appears a few days after fever onset.

Severe Symptoms (Warning Signs)

  • Persistent vomiting and severe abdominal pain.
  • Bleeding: nosebleeds, gum bleeding, blood in stool or vomit.
  • Difficulty breathing or rapid breathing.
  • Extreme fatigue and restlessness.
  • Signs of shock: cold clammy skin, weak pulse, low blood pressure.

Immediate medical attention is essential for severe dengue.


Pathophysiology of Dengue

Pathophysiology explains what happens inside the body:

  1. Infected Mosquito Bite → Dengue virus enters bloodstream.
  2. Infection of White Blood Cells (WBCs) → virus multiplies inside immune cells.
  3. Immune Response → cytokines released, causing inflammation.
  4. Increased Capillary Permeability → plasma leaks into tissues, lowering blood volume.
  5. Drop in Platelet Count → increased risk of bleeding.
  6. Shock in Severe Cases → if plasma leakage becomes massive, blood pressure drops (DHF/DSS).

This chain explains the fever, rash, bleeding, and potential shock seen in dengue.


Diagnosis of Dengue

Doctors diagnose dengue by:

  • Clinical assessment: symptoms plus travel/exposure history.
  • Laboratory tests:
    • CBC to check platelet and white cell counts.
    • NS1 antigen test for early virus detection.
    • IgM/IgG antibody tests.
    • PCR to identify serotype.

Treatment of Dengue

There is no specific antiviral drug for dengue. Treatment is supportive:

Mild Cases (Home/Outpatient)

  • Paracetamol (acetaminophen) for fever and pain. Avoid aspirin or ibuprofen because they increase bleeding risk.
  • Hydration: Drink lots of fluids—oral rehydration solution (ORS), coconut water, fresh juices, clear soups—to prevent dehydration.
  • Rest: Adequate rest supports immune recovery.

Severe Cases (Hospitalization)

  • IV fluids to maintain blood pressure.
  • Monitoring of vital signs and blood counts.
  • Blood or platelet transfusions if necessary.
  • Oxygen therapy if breathing difficulties arise.


Home Remedies & Preventive Tips for Dengue

While there is no cure, certain home remedies can support recovery and help prevent complications. These remedies focus on boosting hydration, supporting the immune system, and naturally maintaining platelet levels. They are supportive, not replacements for medical care.

1. Papaya Leaf Extract

Papaya leaf juice is widely used in traditional medicine to support platelet count in dengue patients.

  • Crush a few fresh papaya leaves, extract the juice, and drink 2–3 teaspoons twice a day.
  • Studies suggest it may help raise platelet counts, though evidence is still limited.

2. Giloy (Tinospora cordifolia)

Giloy is an Ayurvedic herb believed to boost immunity and reduce fever.

  • Boil a few giloy stems in water and drink as a herbal tea once or twice daily.

3. Turmeric Milk

Turmeric has anti-inflammatory properties.

  • Mix half a teaspoon of turmeric powder in warm milk. Drink once daily to aid recovery.

4. Fresh Fruit Juices

Vitamin-rich juices, especially those high in vitamin C, help strengthen immunity:

  • Orange juice, pomegranate juice, guava, kiwi, and amla (Indian gooseberry) are excellent.

5. Coconut Water

Coconut water is a natural electrolyte drink that prevents dehydration caused by high fever and vomiting.

  • Drink 1–2 glasses daily during illness.

6. Fenugreek (Methi) Leaves Tea

Fenugreek leaves help reduce fever and soothe pain:

  • Boil fenugreek leaves in water, strain, and drink the tea once or twice daily.

7. Maintain Good Hydration

Dehydration is a major risk in dengue. In addition to ORS, plain water, soups, and broths should be consumed frequently.

8. Rest and Sleep

Adequate rest allows the body to fight the virus effectively. Avoid strenuous activities during recovery.


Preventing Dengue at Home

Since dengue spreads via mosquito bites, prevention is better than cure:

  • Remove stagnant water: Empty and clean water storage containers, flower pots, buckets, and old tires weekly.
  • Cover water tanks and use mosquito screens.
  • Wear protective clothing: Long sleeves and full-length pants reduce skin exposure.
  • Use mosquito repellents: On skin and indoors.
  • Install screens or nets: Especially on doors, windows, and over beds.
  • Community participation: Encourage neighborhood clean-up drives.

Complications of Dengue

If untreated, dengue can progress to:

  • Dengue Hemorrhagic Fever (DHF): Severe bleeding, low platelets, plasma leakage.
  • Dengue Shock Syndrome (DSS): Dangerous drop in blood pressure and organ failure.
  • Rare complications: Liver inflammation, heart issues, neurological problems.

Timely diagnosis and supportive care can prevent these outcomes.


Recovery from Dengue

Most people recover in 2–4 weeks. Fatigue can linger, but good nutrition, hydration, and rest speed recovery. Those who have had dengue once should be extra careful to avoid future mosquito bites because secondary infections can be more severe.


Conclusion

Dengue is a major public health challenge but one that can be managed with awareness and timely action. It is caused by the dengue virus (DEN-1 to DEN-4) transmitted through the bite of infected Aedes aegypti mosquitoes. Symptoms include high fever, severe headache, joint pain, rash, and, in severe cases, bleeding and shock. While there is no specific antiviral treatment, supportive measures—paracetamol for fever, plenty of fluids, and rest—are effective.

Home remedies such as papaya leaf extract, giloy tea, turmeric milk, and vitamin-rich juices can support recovery by boosting immunity and maintaining hydration and platelet counts. Preventing mosquito bites and eliminating breeding grounds remain the most powerful tools against dengue.

With a combination of medical care, supportive home remedies, and preventive action, individuals and communities can reduce the impact of dengue and protect their health.